Researchers of the University Medical Center Göttingen, in collaboration with the Cluster of Excellence "Multiscale Bioimaging" (MBExC) as well as the German Center for Neurodegenerative Diseases (DZNE) have succeeded in creating neuronal networks with complex functions of the human brain from human induced pluripotent stem cells.  These so-called Bioengineered Neuronal Organoids (BENOs) are suitable for a more precise investigation of the loss of learning ability and memory in neurodegenerative diseases.

The scientists* have published their development in Nature Communications:
Zafeiriou MP, Bao G, Hudson J, Halder R, Blenkle A, Schreiber MK, Fischer A, Schild A, Zimmermann WH Developmental (2020) GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids, Nat Commun, 11, 3791. DOI: 10.1038/s41467-020-17521-w or https://rdcu.be/b5VTo

Source:
https://idw-online.de/de/news753146