The research will focus on 3D models of human tissue designed to offer a replacement for animal testing. These special cell cultures, known as organoids, can be cultivated to resemble individual organs both in function and structure. They open a new window into understanding and treating human diseases, and, in some areas, offer a wider scope of possibilities compared to the analysis of individual cells or animal testing. The challenge lies in developing organoids that resemble human organs as
closely as possible in terms of maturity and complexity, i.e. “micro-organs“ with their own vascular or immune systems.

Six research and two cross-sectional projects are planned on the intestine, lung, heart, brain, liver, and the neuromuscular connection. According to the initiators, the basis is always human cells.

The Einstein Foundation will provide financial support amounting to €5.3 million until the end of 2026 but will make part of its funding subject to the Center's positive interim assessment by the Foundation's independent research board in 2024. The necessary funding will be made available by the State of Berlin in addition to the Einstein Foundation's basic budget.

Source and more information:
https://www.einsteinfoundation.de/en/media/press-releases/2021/15062021-0621/
https://www.aerzteblatt.de/nachrichten/124782/Neues-Einstein-Zentrum-soll-Alternativen-zu-Tierversuchen-entwickeln