Organ-on-chip systems with patients' own cells could enable personalized therapies.
Graphic: Johannes Dornhof and Andreas Weltin, IMTEK.
The use of a patient's own stem cells to replicate original tumors in disease models will make it possible in the future to offer personalized therapy outside the body, especially if resistance develops, the researchers explain.
Original publication
Dornhof, J., Kieninger, J., Muralidharan, H., Maurer, J., Urban, G. A., Weltin, A. (2022): Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures. In: Lab on a Chip, 22 (2). DOI: 10.1039/d1lc00689d.
Source and further information:
https://kommunikation.uni-freiburg.de/pm/2022/neues-organ-on-chip-system-ermoeglicht-praezise-stoffwechsel-ueberwachung-von-3d-tumorgewebe-ausserhalb-des-koerpers