The research team, led by Prof. Andreas Bausch and Dr. Maximilian Reichert, has succeeded in reproducing the morphology of the tumor with its complex duct-like structures. The model enables them to follow individual growth phases of the pancreatic tumor to enable more targeted treatment of this disease.
Original publication:
Randriamanantsoa, S., Papargyriou, A., Maurer, H.C. et al. (2022). Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids. Nat Commun 13, 5219. https://doi.org/10.1038/s41467-022-32806-y