Researchers at the Universities of Mainz and Jena want to develop special nanoparticles that can transport drugs to the liver in a targeted manner. Supported by artificial intelligence, drug-loaded nanoparticles will be modulated in such a way that they can selectively accumulate in certain liver cells and release their active ingredients there.

Scientists at the University of Tübingen want to develop human models of the immune system in order to better understand the interaction between cancer cells and immune cells. Organ-on-chip and organoid models are being used for this purpose.

At the Technical University of Illmenau, for example, new techniques are being used to better assess the quality and maturity of brain organoids at an early stage. In addition to human organoids, new types of mathematical modeling and artificial intelligence are being used.

A team of researchers at Heidelberg University wants to use new engineering approaches, automated production methods and machine learning to better map the complexity of cells and interactions between organs and improve the quality of organoid models, making them reliable and therefore clinically relevant.

Researchers at Friedrich Schiller University Jena want to use synthetic biology to develop therapeutic microorganisms against multi-resistant pathogens.

Further information can be found at:
https://www.carl-zeiss-stiftung.de/themen-projekte/ausgewaehlte-projekte/life-science-technologies-synthetik