Tuesday, 29 April 2025 14:08

In vitro: e-cigarettes could promote atherosclerosis to a lesser extent than tobacco cigarettes Featured

With the help of in vitro tests, American scientists have been able to observe that it is not nicotine that is responsible for the atherosclerotic effect of tobacco smoking, but presumably the countless other harmful substances that enter the circulation through the inhalation of combustion products.


For their investigations, the researchers used a test consisting of a collagen matrix covered with endothelial cells. The researchers applied a nutrient solution of human plasma to this layer together with monocytes that they had isolated from the blood of volunteers.

After 48 hours, they examined how many monocytes, transformed into macrophages, had migrated into the collagen layer and how many of them had turned into foam cells - storage sites for LDL cholesterol and thus starting points for the formation of atherosclerosis. There were far fewer in subjects who had smoked e-cigarettes.

Source:
https://www.aerzteblatt.de/news/e-zigaretten-fordern-atherosklerose-weniger-stark-als-tabakzigaretten-dbfff4fe-34b9-482a-8f7e-ecdb4b9eb57d