Monday, 13 October 2025 11:14

Partnership to validate developmental toxicity assay Featured

The American company Charles River Laboratories International as well as the Dutch biotechnology company Toxys recently announced their intention to collaborate on the validation of the human stem cell-based in vitro assay ReproTracker. The assay can be used to quickly and reliably identify developmental toxicity risks in new drugs and chemicals without the use of animal testing.

The standardized ReproTracker® laboratory test is used to investigate whether chemical compounds disrupt early embryonic development. It records the most important cellular events in human stem cell differentiation and early embryonic development. ReproTracker can be used as an early-stage developmental toxicity screening platform and as an alternative to animal testing for tissue and organ malformations.

Sources and further information:
https://toxys.com/blog/2025/10/08/press-release-charles-river-and-toxys-announce-collaboration-to-validate-the-use-of-nams-for-developmental-toxicity-testing/
https://toxys.com/reprotracker/