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The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is once again accepting applications for the “CAAT Reduction Grant 2026” (CAAT Grant for the Reduction of Animal Testing) and the “CAAT Humane Education Grant 2026” (CAAT Grant for Humane Education). Researchers and educators worldwide are invited to apply.

The European Union Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) runs a testing facility dedicated to the development, validation, and standardization of in vitro methods. Researchers and organizations can now apply for access to this state-of-the-art, automated facility.

At end of June, the Federal Ministry of Research, Technology, and Space (BMFTR) announced its funding program “e2Health – In Silico Research for the Medicine of the Future.” It supports the development and further advancement of in silico methods, software tools, as well as AI technologies for health research.

An international research team at the Center for Photon Research at Paul Scherrer Institute (PSI), led by Dr. Goran Lovric, has succeeded in virtually staining tissue samples using high-resolution micro-computed tomography (µCT) and artificial intelligence. This provides results similar to those of conventional histology methods used in medical diagnostics and research, in which tissue is first cut into extremely thin sections and then stained, for example, to highlight organelles or cells in order to study tissue changes.

The Innovative Health Initiative (IHI) has announced its 13th call for proposals. It aims to support innovators in the healthcare sector in reducing the use of animals in drug safety studies and combating diseases related to aging and the immune system.

Researchers at the RCSI University of Medicine and Health Sciences in Dublin, Ireland, have developed an artificial model of the mitral valve that faithfully replicates the valve’s complex mechanical behavior in the human heart. The study could help researchers better understand heart valve diseases and develop new treatment approaches.

Quantitative Systems Pharmacology (QSP) models play a central and increasingly important role in clinical development. They combine biology, pharmacology, and mathematics to simulate the interactions between drugs and the complex human biological system on a computer.

Using a cellular assay, a British-Danish research team led by Prof. Holm H. Uhlig of the Centre for Human Genetics at the University of Oxford, UK, has confirmed that neutralizing autoantibodies can be responsible for chronic inflammatory bowel disease in certain cases.

On June 15, the National Institutes of Health (NIH) announced the establishment of the “Office of Research Innovation, Validation, and Application” (ORIVA). ORIVA will coordinate NIH-wide efforts to develop, validate, and scale “New Approach Methodologies” (NAMs), including 3D models of human tissue, computer-based tools, and other animal-free methods that can better reflect human biology.

Poland: NAMs.Network Initiative

Monday, 15 June 2026 09:57

The Polish research and technology company QSAR Lab has developed the open-access database NAMs.network. The developers’ goal was to make knowledge about New Approach Methodologies (NAMs) for hazard characterization easier to find, understand, and use.

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