News archive
Genotype of CHO Cells Sequenced
Friday, 12 August 2011 20:21In the 1960s CHO cells from the ovaries of the Chinese hamster were isolated and cultivated. These cell cultures are important production strains for the pharmaceutical industry. Now, for the first time, the genotype of a CHO strain has been sequenced.
Mitochondria from iPS stem cells mutate particularly frequently
Wednesday, 10 August 2011 20:19Researchers from the Max Planck Institute of Molecular Genetics have discovered that mutations occur in the iPS cell´s genome during re-programming of induced pluripotent stem cells (iPS). Mitochondria are particular affected by this.
OECD officially approves guideline based on “Extended One Generation Reproductive Toxicity Study”
Saturday, 06 August 2011 20:17Harmful reproductive toxicology experiments must no longer be performed on two animal generations.
Virulence of Toxoplasma gondii in human cell culture is predictable
Friday, 05 August 2011 20:15Toxoplasma gondii can induce toxoplasmosis in humans. In a completed study funded by the Swiss Foundation 3r, scientists from the Pasteur Institute, Brussels, have developed a method by which they can test the virulence of Toxoplasma gondii in vitro.
Researchers are prize winners of the German nationwide competition “365 Landmarks in the Land of Ideas” for their “in vitro pyrogen test”
Friday, 22 July 2011 20:03The Clinical Research Laboratory of the Department of Thoracic and Cardiovascular Surgery at the University Hospital Tübingen and the Interfaculty Centre for Pharmacogenomics and Pharma Research are amongst this year’s prize winners in the German nationwide competition “365 Landmarks in the Land of Ideas”. The lab’s three award recipients, Prof. Dr. Albrecht Wendel (inventor of the innovative method), Prof. Dr. Hans Peter Wendel and Dr. Stefan Fennrich, were awarded the prize in recognition of their development of the in vitro pyrogen test “PyroDetect”.
Cardiotoxicity: model for more exact research of drug induced heart problems
Friday, 22 July 2011 19:09The model combines two new technologies, tissue engineering using stem cells and impedance-based real-time cell monitoring using the xCELLigence Cardio instrument from ROCHE.
Switzerland: cardiopulmonary simulator replaces animal experiments
Wednesday, 20 July 2011 19:06A development team at the nanomedical centre of the private non-profit company CSEM in Landquart, Switzerland, in collaboration with the Landquart company Fuchs Engineering GmbH, has developed a high-tech apparatus called “TestChest”. The apparatus allows simulations of unprecedented consistency and diversity for use in the field of cardiac and pulmonary medical training, and provides a replacement method for animal tests.
Immobilisation and investigation of three-dimensional liver cells on bio-chips
Tuesday, 19 July 2011 19:04New and very promising scientific findings concerning toxicity tests on cells have been made by means of electrochemical measurements using electrochemical sensors with the help of IMOLA-IVD measurement systems and three-dimensional micro-tissue.
Artificial trachea from stem cells successfully implanted
Friday, 15 July 2011 19:02A Swedish surgery team has successfully implanted a trachea implant colonised with stem cells. The scientists did not require a donor organ, as they had also created an artificial scaffold, which was not the case in previous transplantations.
Fraunhofer ILT produces biomimetic hybrid structures for regenerative medicine
Tuesday, 12 July 2011 18:51Researchers at the Fraunhofer Institute of Laser Technology (ILT) in Aachen, Germany, and other Fraunhofer institutes have used a special laser technique to create hybrid biomimetic matrices which can serve as basis for scaffold and implant structures on which cells can grow.
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