A study published in Nature suggests that lab-grown organoids can help predict the treatment effects of genetic drugs made from RNA for people with rare diseases.
Researchers at the University of Basel used the method of high-throughput metabolomics to simultaneously test the effects of more than 1,500 active substances on the metabolism of cells.
The Foundation for the Promotion of Research into Alternative and Complementary Methods to Animal Experiments (Stiftung zur Förderung der Erforschung von Ersatz- und Ergänzungsmethoden zum Tierversuch, set Foundation for short) is suspending its funding round this year.
Using a brain organoid model, a research team from the Department of Biomedical Engineering at Tufts University in Medford, Massachusetts, in collaboration with the University of Oxford, has observed that neuronal injury can reactivate latent herpes type 1 viruses, leading to the production and accumulation of ß-amyloid and phosphorylated tauproein, which promotes synaptic dysfunction and neurodegeneration.
A research team led by Prof. James Hickman of Hesperos Inc., in collaboration with the University of Central Florida in Orlando, has developed a novel multi-organ MPS model to investigate the efficacy and off-target toxicity of naloxone in combination with opioids.
The US Food and Drug Administration (FDA) has published a draft guidance document on the use of artificial intelligence for the safety assessment of drugs and biological products.
A research team from the Icahn School of Medicine at Mount Sinai, New York and Memorial Sloan Kettering Cancer Center, New York has developed an AI program that uses routine blood tests to predict which patients will respond to a particular immunotherapy.
A research team led by Prof. Dr. Jörg Tatzelt from the Department of Biochemistry of Neurodegenerative Diseases at Ruhr-Universität Bochum has used new in-vitro and cell culture models to show that a lipid anchor on the outside of nerve cells prevents the prion protein from clumping together.
For the first time, a team from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the NCT Heidelberg has succeeded in cultivating stable tumor organoids directly from blood samples of breast cancer patients.
Since 2017, the French Embassy in Germany, in partnership with the Franco-German University of Applied Sciences, has been awarding the Forcheurs Prize to honor promising Franco-German scientific collaborations between a tandem of young researchers (under 45 years of age) in the field of chemistry, pharmacology or at the interface between chemistry and health. The prize is under the patronage of Jean-Marie Lehn, winner of the Nobel Prize in Chemistry.