News archive

"Brain wave measurements" in brain organoids

Wednesday, 04 September 2019 15:41

American researchers have measured electrical activity in miniature brains, which, according to the researchers, are supposed to be similar to brain waves in premature infants.

Using the novel organ-on-a-chip technology, scientists from the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB as well as from the University of Tübingen have succeeded in simulating the complexity of the human retina in a microphysiological system. The retina-on-a-chip model can help to investigate eye diseases and test the harmful side effects of drugs on the eyes.

In two new projects, researchers from the Institute of Pharmaceutical Technology at Braunschweig University of Technology will develop human nasal mucosa and cornea models in order to achieve more reliable results and avoid animal experiments. In oneof the projects, a corneal model will be further developed to fulfil the high requirements of drug testing for eye diseases. The second project deals with the simulation of a human nasal mucous membrane on a chip system.

Using cell cultures a researcher team from the Heinrich Heine University in Düsseldorf has investigated, what effects carbon nanoparticles have on cells. The results were published in the journal Scientific Reports.

Frankfurt: 7th Galenus Workshop

Thursday, 22 August 2019 11:19

Under the title "Human in vitro models - biology meets technology", the Institute of Pharmaceutical Technology in cooperation with the Buchmann Institute for Molecular Life Sciences of the Goethe-University Frankfurt will hold a two-day conference with a subsequent lab course.

The Department of Justice, Consumer Protection and Anti-Discrimination of the Senate together with the State Office for Health and Social Affairs and the Association of researching pharmaceutical companies (vfa) is presenting the this years research prize for the promotion of the development of alternative and complementary methods to animal testing. The prize money amounts to euros 30,000,-. Deadline is the 30th of September.

This year's "Replacement of the Year" issue examines the current development and acceptance of a testing strategy to replace rodents in tests for brain development disorders (developmental neurotoxicity tests). Scientists have been working for some time with regulatory authorities such as the European Food and Safety Agency (EFSA) on a cost-effective testing strategy based on a reliable in vitro test battery to identify DNT hazards to reduce exposure to these chemicals. For this purpose, the complex processes of brain development are to be broken down into individual spatially and temporally separate development steps. For each step, individual tests are to be developed.

Between 9 September and 6 December of this year, applicants may apply or be nominated for the LUSH Prize 2020. The prize is worth a total of 350,000 British Pound and honours researchers and individuals in the five categories Science, Young Scientists, Training, Public Relations and Lobbying.  

Robotic fish for environmental tests

Tuesday, 06 August 2019 20:57

Scientists from the University of Magdeburg together with researchers from Dresden, Jena, Stuttgart and Estonia are working on a project to replace legally prescribed animal experiments in European hydropower plants by robotic fish. With this kind of artificial fish they want to gain information about flow conditions and expected harm to real fish in European river power plants.

Beating Heart Chamber from the 3D printer

Monday, 05 August 2019 08:36

With help of the 3D printer, American researchers from the Carnegie Mellon University in Pittsburgh have created a left heart chamber consisting of collagen and myocardial cells, which began to beat on its own within a few days. The scientists have described their development in the magazine "Science".