For years, scientists have already produced epidermis from biopsy samples, but the current study is a further development. The researchers used reprogrammed skin cells that For years, scientists have already produced epidermis From biopsy samples, but the current study is a further development. The researchers used reprogrammed skin cells that allow the production of an unlimited number of cells mainly present in the epidermis, thus allowing the use of animal-free methods on a large scale.
The researchers have published their results in the journal Stem Cell Reports.
Source (in German):
http://www.innovations-report.de/html/berichte/biowissenschaften-chemie/menschliche-haut-aus-stammzellen-hergestellt.html
Original literature:
Anastasia Petrova, Anna Celli, Laureen Jacquet, Dimitra Dafou, Debra Crumrine, Melanie Horn, Matthew Arno, Carl Hobbs, Aleksandra Čvoro, Panagiotis Karagiannis, Liani Devito, Richard Sun, Lillian C. Adams, Robert Vaughan, John A. McGrath, Theodora M. Mauro email, Dusko Ilicemail (2014): 3D In Vitro Model of a Functional Epidermal Permeability Barrier from Human Embryonic Stem Cells and Induced Pluripotent Stem Cells. StemCellReports 2: 1-15. DOI: http://dx.doi.org/10.1016/j.stemcr.2014.03.009