With a digital kick-off event today and tomorrow, the new Horizon 2020 project called SIMCor get underway. The goal is to provide manufacturers of cardiovascular implantable devices an open, reusable, cloud-based platform for in silico testing. Thus, the development and approval of cardiovascular implants will be accelerated.

Scientists from Würzburg and the United States have produced an atlas on the direct interactions between the new coronavirus and the cells it infects.

Researchers from the Ruhr-Universität Bochum and from the Vrije University Amsterdam have investigated the development of amyloid-β protein deposits using infrared microscopy. They have gained important insights.

This year, the state of Rhineland-Palatinate is again awarding a research prize for the promotion of alternatives to animal experiments.

Corona particles in the olfactory mucosa

Wednesday, 02 December 2020 15:16

A research team from Charité-Universitätsmedizin Berlin, Humboldt University Berlin, and other scientists* has succeeded in detecting the Sars-Cov2 virus in neuroanatomical structures that connect the eye, mouth, and nose with the brain stem. Using special staining and electron microscopic imaging, they were able to visualize and photograph intact coronavirus particles in the olfactory mucosa, where the virus was most commonly found.

A ban on animal testing for cosmetics has been in force in the EU since 2013. Since then, neither the conduction of corresponding tests nor the trade with corresponding products is allowed. But this milestone of animal protection is now in danger.

Newsletter November 2021

Sunday, 29 November 2020 17:28

Here, we provide information about carcinogenicity tests – tests to determine whether a substance can cause cancer or not. The knowledge is necessary to classify correctly, prohibit their use, provide limitations for their application or at least offer safety advice/ warnings. For example, the use of the pesticide Linuron has been banned in the EU since 2018, among other things because of its carcinogenic properties.1, 2

Up to now, such tests have been performed on rodents. For some time, regulatory authorities, the Industry and academia agreed, that animal testing should be no longer mandatory – primarily because at the time of the beginning of such tests there is already sufficient information available from animal experiments to estimate a possible risk of cancer in humans. However, the corresponding regulation is still not deleted and these tests, which are to a large extent highly stressful for the animal, are continued.

To date, there is no standardized database for replacement methods that provides an overview of all methods, research results and application purposes. This is now changing - the federal government is funding the conceptual development of such a database in a first step until 2021 with 3 million euros.

Today, the 39th Animal Welfare Research Prize of the Federal Ministry of Food and Agriculture (BMEL) was awarded. Dr. Anne-Katrin Rohlfing from the Department of Cardiology and Angiology at the University Hospital of Tübingen was honored for her new method of producing genetically modified platelets for basic research and testing.

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