Prof. Dr. Wolfgang Schamel from the Institute of Biology III, the Cluster of Excellence BIOSS Centre for Biological Signalling Studies at Albert-Ludwigs-University Freiburg and the Center for Chronic Immunodeficiency at the University Medical Center Freiburg is the coordinator of the EU-funded project SYBILLA (Systems Biology of T-cell Activation in Health and Disease). From 2008, 17 partners from science and industry have worked together to understand the T cell as a system.

Now the project findings are available for the public as an interactive online simulation. Being able to simulate signal pathways within the cell allows the development of new therapeutic approaches for cancer, autoimmune disorders and infectious diseases.

This simulation or a more developed system may also, together with expert systems for bioavailability, provide the basis for an integrated simulation that can be used to replace animal experiments in the future.

For more information: http://www.pr.uni-freiburg.de/pm/2013/pm.2013-12-05.339-en