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Thursday, 02 February 2023 13:45

In vitro: stronger myocardial damage caused by corona variant BA.5 Featured

Using human cardiac muscle cells, researchers from the Institute of Molecular Virology at Ulm University Hospital have found out that the BA.5 subvariant of the coronavirus SARS-CoV-2 has a higher infectivity and cell-damaging effect than other subvariants.


The researchers attribute these properties to additional mutations in the spike protein.

Original publication:
Nchioua, R., Diofano, F., Noettger, S. et al. (2022). Strong attenuation of SARS-CoV-2 Omicron BA.1 and increased replication of the BA.5 subvariant in human cardiomyocytes. Sig Transduct Target Ther 7, 395. https://doi.org/10.1038/s41392-022-01256-9

More information:
https://www.aerzteblatt.de/nachrichten/140700/Omicronsubvariante-BA-5-schaedigt-Kardiomyozyten-staerker?rt=8b1a674cf080a3174d3d19d876630244


 

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