A team of researchers from Innsbruck has developed a three-dimensionally printed tumor model with a human tissue microenvironment. The aim is to study the development of tumors in even greater detail and to test cancer drugs for their effectiveness.

As Nature writes in its current issue, researchers have used the artificial intelligence network called AlphaFold to predict the structures of about 200 million proteins from 1 million species, covering almost all known proteins on the planet.

BMBF supports a mini lung model

Friday, 29 July 2022 09:14

A team of researchers at Helmholtz Center Munich has received funding from the German Federal Ministry of Education and Research (BMBF) for an in vitro method to directly measure the transport of active substances from the lungs into the blood.

This year's Animal Welfare Award goes to Dr. med. Michael Karl Melzer from the University Hospital Ulm as well as to the "Würzburg Initiative 3R (WI3R)". All award winners are honored for their efforts to replace or at least reduce animal experimentation with new animal-free methods.

Just recently, the first therapeutic successes with the gene scissors CRISPR/Cas have been announced. Now, a team of researchers from Tel Aviv University (TAU) has reported, that the technique leads to a destabilization of the genome in cells, which in turn can trigger cancer.

Medical devices for advanced therapies are gene therapies, somatic cell therapies, or the use of genetically modified tissues in cases where conventional therapies fail. Such medical devices must also be tested for safety and possible immune reactions in the same way as drugs or other medical devices.

This year's Saarland Prize for Alternative Methods to Animal Testing was awarded to Dr. Albert Omlor of Homburg University Hospital and Dr. Jennifer Herrmann of the Helmholtz Institute for Pharmaceutical Research.

The German Federal Ministry of Education and Research (BMBF) has issued the "Guideline for the Funding of Preclinical Confirmatory Studies and Systematic Reviews". In addition to necessary systematic reviews and meta-analyses on preclinical research topics, it is also possible to apply for funding to use scientifically recognized "alternative methods".

Applicants are invited to submit project proposals addressing missing key elements to implement New Approach Methodologies (NAMs, new non-animal method approaches) in EFSA's scientific assessment process. The aim is to use this to improve decision-making in the food and feed sectors.

A new survey conducted by the EU reveals gaps in knowledge about the animal-free production of serums, antibodies, and enzymes.  

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