Allergan Inc. (NYSE:AGN) got the approval for a fully in vitro, cell-based assay for use in the stability and potency testing of BOTOX® (onabotulinumtoxinA) and BOTOX® Cosmetic from the United States Food and Drug Administration (FDA).

Communicating Biological Barriers

Friday, 27 May 2011 17:53

With "InLiveTox", a project supported by the European Union, scientists for the first time interconnect three biological barriers in one sigle "in vitro model". With that they want to simulate nature related conditions like in human body.

InvitroJobs will present scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principle of Russel & Burch (reduce, refine, replace).
The series will continue with the research group "Experimental Cell- and Tissue Technology", which is within the working group "Molecular Haemostaseology" at the University Hospital of Jena. The presentation is followed by an interview with Dr. rer. nat Sandy Mosig.

In future it will be possible to produce economically antibodies, holding a key role in the investigation of biological and medical questions, without the use of animals in large numbers.

For the first time ever in the world, researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have produced a blood vessel from stem cells and then used it in an operation on a 10-year-old girl at the Sahlgrenska University Hospital.

Researchers in Bochum have produced an antibody that allows them to distinguish the numerous types of stem cells in the nervous system better than before.

Columbia Engineers Patch A Heart

Monday, 09 May 2011 17:01

Researchers at Columbia Engineering have established a new method to patch a damaged heart using a tissue-engineering platform that enables heart tissue to repair itself.

Cultex Laboratories GmbH, located in the Medical Park Hannover, has developed the CULTEX® RFS module, a precision instrument for direct exposure of cells from the respiratory tract. Mimicking the in vivo situation, bronchial epithelial cells for example can be treated with a wide range of test substances (individual gases, gas mixtures, particulate aerosols etc.).

Starting with this article, InvitroJobs will present scientists and their innovative research in a regular feature called “Working Group – a Portrait”.
We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principle of Russel & Burch (reduce, refine, replace). We start with two research groups from the Clinical Research Laboratory of the Paediatric Cardiac Surgery Department of Tübingen University Hospital, “Haemocompatibility” and “Pyrogen assay”. The introduction is followed by an interview with Dr. med. Stefan Fennrich.

The Bavarian Research Foundation is supporting a research project under the name of COSIR (Combination of Chemical-Optical Sensors with Image Recognition) with the goal of developing a system for continuous imaging of cell cultures with simultaneous oxygen and pH value measurements of the sample without any human intervention.