Pancreatic cancer undone in human cells

Wednesday, 06 October 2021 08:59

A team of researchers at Purdue University in West Lafayette, Indiana, engineered an acinar-on-chip (PAC) from reprogrammed pancreatic cancer cells and induced PTF1a gene expression in the cells. They observed that the cells transitioned to a more normal and differentiated acinar phenotype. The model can be used to study the development and progression of pancreatic cancer.

Jena: Research to combat infectious diseases

Thursday, 23 September 2021 09:00

As part of the EU project Inno4Vac (Innovations to accelerate vaccine development and manufacture), the "Inspire" working group from Jena University Hospital will develop immunocompetent organ models. InVitro+Jobs spoke with the head of the Inspire working group at Jena University Hospital, private lecturer Dr. Alexander Mosig.

With the help of its own Innovation Task Force (ITF), the European Medicines Agency (EMA) aims to help developers to replace, reduce and refine animal testing during the development, manufacture and testing of human and veterinary medicines.

October 2021: EPAA Annual conference

Monday, 27 September 2021 12:20

The annual EPAA event on October 27th, will give participants insight into EPAA’s achievements in 2021, announce the EPAA Refinement Prize winner, and discuss our role in the EU chemical strategy for sustainability.

ECEAE Prize for animal-free antibodies

Wednesday, 22 September 2021 12:19

To raise awareness about the advantages of animal-free produced antibodies and promote their development and application, the European Coalition to End Animal Experiments (ECEAE) is announcing for the first time a Prize for animal-free antibodies. The aim of this prize is to highlight the versatility and superiority of animal-free antibodies and encourage their acceptance and use for research and therapeutic purposes.

To find out more precisely how the SARS-CoV-2 virus manages to evade immune defenses and replicate in the cells of patients, an international research team involving the Technical University of Munich broke new ground with artificial intelligence. They succeeded in compiling the most comprehensive and detailed overview to date of all the 3D structures of the virus proteins available worldwide. In a database, this information is publicly available for research.

The EU Parliament has called on the EU Commission to draw up an EU-wide action plan for a phase-out of animal experiments.

Good news from Berlin: the State Animal Welfare Commissioner, Dr. Kathrin Herrmann, has offered two animal welfare awards for this year with a total sum of 60,000 euros. The deadline is October 17, 2021.

The 11th World Congress on Alternatives and Animal Use in the Life Sciences was held between August 23 and September 3, 2021. It was supposed to have taken place in Maastricht last year, but was postponed by one year due to Corona, and was organized virtually. More than 1,000 participants from academia, industry, regulatory authorities, and NGOs had registered for this event, which was held under the motto "3Rs in transition - from development to application". But have the processes already reached the final stage of the application?

Zurich: 3D organoids in space

Monday, 30 August 2021 12:03

Oliver Ullrich, professor of anatomy at the University of Zurich (UZH), biologist Cora Thiel as well as the company Airbus Defence and Space GmbH are using microgravity in space to cultivate three-dimensional organ-like tissues from human adult stem cells.