The Einstein Center 3R is a Berlin science initiative aiming to develop alternative methods to animal testing. The authors want to provide a differentiated picture of the current state of research in an understandable way using examples to give an insight into daily research.
With a total endowment of 110,000 euros rewarding 3 categories, the DVES prize is one of the best endowed prizes in Europe entirely dedicated to the most advanced, most convincing scientific and technological knowledge for alternatives to animal experiments.
In its Pharmacopoeia, the United States has recognized synthetic alternatives to the blood of horseshoe crab. This allows synthetic alternatives such as the recombinant factor C test to be used as evidence for the quantification of endotoxins in medical products.
Researchers from the Department of Drug Delivery across Biological Barriers at Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) have developed a hair follicle model for testing the effectiveness of new drug candidates against relevant pathogens.
The Indian Pharmacopoeia Commission (IPC) has made a change to the Indian Pharmacopoeia with effect from July 1, 2024 and has discontinued the Target Animal Batch Safety Test (TABST) since the effective date.
A researcher team headed by Prof. Ben Shofty from University of Utah and Assistant Prof. Eleonora Bartoli from Baylor College of Medicine in Houston has investigated the way different areas of the brain work together to enable creative thinking.
Researchers from Eawag in Dübendorf, Switzerland, as well as from the Swiss Data Science Center in Lausanne, Switzerland, have trained AI algorithms with a comprehensive ecotoxicological data set. Their machine learning models can predict how toxic chemicals are to fish.
Using a collection of historical human blood samples, researchers from the Institute of Medical Virology at the University of Zurich have discovered that the severity of an infection such as COVID-19 is caused by autoantibodies. These are autoantibodies that neutralize type I interferons (IFN-Is).
The renowned researcher Prof. Milica Radisic from the Institute of Biomedical Engineering at the University of Toronto will be working at the Max Delbrück Center in Berlin-Buch for the next three years with the aim of equipping organoids with blood vessels. This would make them more similar to a real organ in miniature format.
At its 179th meeting in June 2024, the Ph.Eur. Commission adopted 57 revised texts aimed to completely remove the test for fever-inducing substances in rabbits (pyrogen test) from the European Pharmacopoeia (Ph.Eur.). This means that the use of the pyrogen test in rabbits is no longer prescribed anywhere in the regulations.