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The European Animal Testing Directive and the EU Chemicals Regulation (REACH) require that animal testing to assess possible toxicity to humans should only be carried out as a last resort. An association of representatives from industry and non-governmental organizations has discovered that these requirements are not being seriously implemented, resulting in countless animal experiments.

A team of researchers led by Prof. Dr. Konstanze Winklhofer from the Ruhr University Bochum has discovered that the protein NEMO, which is known amongst other things for its role in the innate immune system, has an important function in labeling protein aggregates in the brain to prevent harmful deposits such as those that occur in Parkinson's disease.

By using mass spectrometry to study the proteome in the spinal fluid of Alzheimer's patients, scientist Betty Tijms and her colleagues from the Alzheimer Center Amsterdam, Amsterdam UMC and the University of Maastricht have discovered that there are five different subtypes of Alzheimer's disease. Understanding this heterogeneity is crucial for the development of Alzheimer's drugs.

According to the Science Magazine, the White Coat Waste Project, an interest group dedicated to eliminating taxpayer-funded animal testing in the US, has pointed out that the US Environmental Protection Agency (EPA) no longer explicitly mentions the goal of phasing out mammalian testing by 2035 in its plans.

Saarland Research Prize 2024

Monday, 18 December 2023 15:31

Scientists, research groups, scientific companies and institutions active in Saarland are eligible to participate. The prize money amounts to 10,000 euros and can be divided among up to three prize winners.

Researchers led by Dr. Sasha Mendjan at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences, Vienna, have developed a new multi-chamber organoid that reflects the complex structure of the whole heart.

This year's Animal Welfare Research Prize of the Federal Ministry of Food and Agriculture (BMEL) was awarded to Prof. Dr. Diana Klein from the Institute of Cell Biology (Tumor Research) of the Medical Faculty of the University of Duisburg-Essen. She received the award for her work on the development and application of cell culture models in the field of tumor research.

Prof. Dr. Ellen Fritsche has been appointed as director of the Swiss Center for Applied Human Toxicology (SCAHT) based in Basel.

The German Center for the Protection of Laboratory Animals Bf3R at the Federal Institute for Risk Assessment, Berlin, has published its search engine for finding animal-free methods.

An American-German research team has succeeded in creating a comprehensive database that can be used to assess the relevance of results from NAMs (computer predictions, in-chemico and in vitro tests) with high-quality human reference data.